Actively Recruiting
Effects of CBT and BLT in Youth With Unipolar Depression and Evening Chronotype
Led by The University of Hong Kong · Updated on 2024-04-22
162
Participants Needed
1
Research Sites
155 weeks
Total Duration
On this page
Sponsors
T
The University of Hong Kong
Lead Sponsor
C
Chinese University of Hong Kong
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this prospective randomised controlled trial is to examine the effects of cognitive behavioural therapy and bright light therapy in youths with unipolar depression and evening chronotype. The main questions it aims to answer are: 1. What is the efficacy of CBT-D and CBT-D plus bright light therapy in reducing depression severity in adolescents with depression and eveningness? 2. What are the effects of CBT-D and CBT-D plus bright light therapy on the subjective and objective sleep and circadian measures, as well as the quality of life, daytime symptoms, and functioning (e.g., sleepiness, fatigue)? Participants will participate in 8 weekly group sessions of CBT-D intervention based on the well-established CBT elements for treating depression. Concurrently participants will also be asked to wear a portable light device at home for 30 minutes daily for seven weeks, starting from the second week of the group intervention. Participants in the CBT-D only group will receive a placebo light via the device, whereas participants in the CBT-D plus light therapy group will receive the active bright light via the device.
CONDITIONS
Official Title
Effects of CBT and BLT in Youth With Unipolar Depression and Evening Chronotype
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chinese aged 12-20 years old
- Written informed consent given by the participant and parent or guardian if under 18
- Ability to follow the study protocol
- Diagnosed with depressive disorders according to DSM-5
- Score of 40 or higher on Children's Depression Rating Scale (CDRS-R)
- Score of 41 or less on Horne-Östberg Morning-Eveningness Questionnaire (evening chronotype)
- Sleep onset at or after 11:15 pm (age 12), 11:30 pm (ages 13-14), or midnight (ages 15-20) at least 3 nights per week in past 3 months
You will not qualify if you...
- Current substance abuse or dependence
- Current or past manic/hypomanic episode, schizophrenia spectrum disorders, neurodevelopmental disorders, organic mental disorders, or intellectual disabilities
- Medication changes affecting circadian rhythm in past 3 months (e.g., lithium, melatonin)
- Clinically significant suicidality with plan or attempt
- Participation in another clinical trial within 1 month
- Antidepressant medication started or changed within past 3 months
- Currently receiving structured psychotherapy
- Hearing or speech deficits
- Night shift work
- Trans-meridian flight in past 1 month or during intervention
- Eye diseases such as retinal blindness, severe cataract, or glaucoma
AI-Screening
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Trial Site Locations
Total: 1 location
1
Sleep Research Clinic & Laboratory, Department of Psychology, The University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
S
Shirley X Li, DClinPsy
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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