Actively Recruiting

Phase Not Applicable
Age: 8Years - 80Years
All Genders
NCT06420271

Effects of Cerebellar tACS-iTBS in Ataxia

Led by I.R.C.C.S. Fondazione Santa Lucia · Updated on 2026-02-17

30

Participants Needed

1

Research Sites

87 weeks

Total Duration

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AI-Summary

What this Trial Is About

Ataxia refers to a group of neurological disorders characterized by impaired coordination and balance due to dysfunction in the cerebellum or its connections. Traditional therapeutic approaches for ataxia have shown limited efficacy, prompting researchers to explore alternative interventions. Non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), and intermittent theta burst stimulation (iTBS), have emerged as potential therapeutic options. The aim of this study is to investigate the combined effect of tACS-iTBS on balance functions in ataxia disorders.

CONDITIONS

Official Title

Effects of Cerebellar tACS-iTBS in Ataxia

Who Can Participate

Age: 8Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of ataxia based on clinical assessment and/or neuroimaging findings.
  • Stable medication regimen for at least four weeks prior to the study.
  • Sufficient cognitive ability to understand and comply with study instructions.
Not Eligible

You will not qualify if you...

  • History of seizures.
  • Severe general impairment or concomitant diseases.
  • Intracranial metal implants.
  • Cardiac pacemaker.
  • Pregnancy status.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Santa Lucia Foundation

Rome, Lazio, Italy, 00179

Actively Recruiting

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Research Team

G

Giacomo Koch, Prof.

CONTACT

V

Valentina Pezzopane, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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