Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT07229014

Effects of a Collagen Supplement on Quality of Life, Appetite and Glycaemic Control

Led by King's College London · Updated on 2025-11-14

100

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

Sponsors

K

King's College London

Lead Sponsor

R

Rousselot BVBA

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a clinical trial aimed to investigate if a collagen supplement can improve quality of life, appetite and blood sugar in overweight and obese adults aged 18-65. Hypothesis: Consumption of a collagen supplement for 8 days will improve quality of life and improve glycaemic control in comparison with a placebo in individuals overweight or with obesity with a perceived low quality of life. Participants will be asked to: 1. Consume a collagen peptide supplement for a total of 8 days at a time 2. Fill in questionnaires about quality of life, appetite, mood and energy 3. Wear continuous glucose monitors

CONDITIONS

Official Title

Effects of a Collagen Supplement on Quality of Life, Appetite and Glycaemic Control

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy adults aged 18 to 65 years who are overweight or obese with a BMI of 25 to 40 kg/m2
  • Participants with impaired quality of life based on specific questionnaire scores for energy, mood, and sleep
  • Must have email, internet access, and a compatible smartphone for virtual visits and online questionnaires
  • Willing and able to comply with all study procedures including supplement intake, continuous glucose monitoring for 22 days, meal tests, and questionnaires
  • Willing to take a supplement containing bovine animal products
  • Open to participating in an online interview at the end of the study
Not Eligible

You will not qualify if you...

  • History or presence of uncontrolled or significant pulmonary, cardiac, liver, kidney, endocrine (including diabetes), blood, immune, neurological, psychiatric, or biliary diseases
  • Significant gastrointestinal conditions affecting study evaluation, including inflammatory bowel disease, irritable bowel syndrome, severe constipation, frequent diarrhea, weight loss surgery, gastroparesis, or lactose intolerance
  • Chronic insomnia or diagnosed sleep disorders or medical conditions impacting energy or fatigue
  • Pregnant, planning pregnancy, lactating, or unwilling to use approved contraception if of childbearing potential
  • Known allergy, intolerance, or sensitivity to study product ingredients including bovine products
  • History of cancer in the past two years except non-melanoma skin cancer
  • Recent major trauma or surgery within three months prior to study start
  • Unstable use of medications or supplements that may affect trial outcomes
  • Participation in another biomedical study within 30 days before screening
  • Employment or financial interest in the study sponsor company
  • Conditions interfering with informed consent or study compliance
  • Vegan, vegetarian, or cultural/religious exclusion of bovine products

AI-Screening

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Trial Site Locations

Total: 1 location

1

Metabolic Research Unit (KCL, Waterloo Campus)

London, London, United Kingdom, SE1 9NH

Actively Recruiting

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Research Team

A

Alex Cheok, PhD

CONTACT

A

Ana Rodriguez-Mateos, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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