Actively Recruiting
The Effects of Colorectal Prehabilitation Via Reinfusion or Retention Enema of Ileal Contents Filtrate on the Defecation Functions for the LAR Patients With Ileostomy Before Stoma Closure
Led by The Affiliated Hospital of Qingdao University · Updated on 2024-08-26
154
Participants Needed
1
Research Sites
178 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study was a single-center RCT study to compare the effect of preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon with that of traditional treatment in patients with bowel function after stoma closure.
CONDITIONS
Official Title
The Effects of Colorectal Prehabilitation Via Reinfusion or Retention Enema of Ileal Contents Filtrate on the Defecation Functions for the LAR Patients With Ileostomy Before Stoma Closure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 to 85 years old
- Karnofsky performance status (KPS) 70% or higher, or ECOG score of 2 or less
- Rectal cancer confirmed by preoperative pathology
- Undergoing low anterior resection or low colorectal anastomosis before or after neoadjuvant therapy
- Having a prophylactic ileostomy
You will not qualify if you...
- Unable to complete treatment
- History of anorectal surgery
- Preoperative bowel dysfunction such as diarrhea, irritable bowel syndrome, or functional constipation
- Postoperative anastomotic fistula or stricture
- Pregnant or breastfeeding women
- Uncontrolled seizures, central nervous system disease, or mental disorder history
- Other malignant disease within last 5 years except skin cancer or cervical carcinoma in situ
- Significant active heart disease or recent myocardial infarction
- History of cerebral infarction or hemorrhage within past 6 months
- Organ transplant requiring immunosuppressive therapy
- Serious uncontrolled infections or diseases
- Moderate or severe renal impairment (creatinine clearance ≤50 ml/min)
- Emergency surgery due to tumor complications
- Received study medication or treatment within 4 weeks prior to screening
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
the Affiliated Hospital of Qingdao
Qingdao, Shandong, China, 266000
Actively Recruiting
Research Team
Y
Yanbing Zhou
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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