Actively Recruiting
Effects of Combination Exercise on Fatigability in Veterans With Chronic Kidney Disease
Led by VA Office of Research and Development · Updated on 2026-03-12
30
Participants Needed
1
Research Sites
252 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The VA health care system uses a health promotion-focused model which aims to provide longitudinal care through a patient-aligned care team for Veterans with chronic kidney disease. Since the largest subpopulation of Veterans with chronic kidney disease is comprised of those not requiring dialysis, neuromuscular screening assessments may provide valuable information regarding an individual overall health status and potential for future complications. Furthermore, identifying at risk individuals early in the disease process will allow for the prescription of timely interventions. Exercise strategies such as combination exercise, which uses flywheel resistance plus aerobic exercise, may provide a valuable treatment option for combating neuromuscular dysfunction and functional decline in patients with chronic kidney disease.
CONDITIONS
Official Title
Effects of Combination Exercise on Fatigability in Veterans With Chronic Kidney Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ambulatory individuals aged 50 years or older diagnosed with chronic kidney disease stages 3 and 4 predialysis (eGFR 59-15 ml/min per 1.73m2)
- Control group includes ambulatory individuals without kidney disease (eGFR >60 ml/min per 1.73m2) within the last 12 months
- Ability to speak and read English and be oriented to person, place, and time
You will not qualify if you...
- Adults diagnosed with acute renal failure or injury within the last 12 months
- Non-ambulatory individuals
- Adults who do not use the DC VAMC as their main site for renal care
- Uncontrolled cardiovascular or musculoskeletal diseases
- Other conditions that could make study participation unsafe as determined by the principal investigator
- Orthopedic or joint pain preventing safe participation in the study
- Plans to relocate from the DC metro area within one year, excluding eligibility for the intervention portion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington DC VA Medical Center, Washington, DC
Washington D.C., District of Columbia, United States, 20422-0001
Actively Recruiting
Research Team
J
Jared M Gollie, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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