Study of Cranberry Beverage Effects on Gut Health and Metabolism in Overweight Adults

What this Trial Is About

Researchers are exploring how cranberry supplementation affects metabolic health and gut bacteria in adults who are overweight or obese. The study focuses on understanding changes in blood sugar control, insulin sensitivity, blood fats, and the gut microbiome. It is a randomized, double-blind, placebo-controlled crossover trial designed to clarify cranberrys impact on intestinal health and overall metabolism. Participants will take part in two 12-week intervention periods one involving daily consumption of a 240 ml cranberry beverage and the other a placebo beverage, with a 4-week break between these phases. Before the interventions, there will be a 2-week phase to stabilize lifestyle habits. Some female participants will also undergo liver fat imaging using MRI to assess changes in fat accumulation. During the study, participants will have comprehensive assessments including blood tests for glucose, insulin, and lipid levels, body composition measurements, gut microbiota analysis, and evaluations of inflammation and appetite. These evaluations will occur before and after each treatment period. The total duration includes the lifestyle stabilization, two treatment periods, and a washout phase, with ongoing monitoring of health markers related to obesity and metabolism.

Effects of Cranberry on Gut and Metabolic Health