Study Comparing Three Ventilation Modes on Brain Pressure and Carbon Dioxide Levels During Bariatric Surgery

What this Trial Is About

This research aims to explore the clinical importance of different ventilation modes in patients undergoing bariatric surgery. It focuses on whether various ventilation patterns affect intracranial pressure and the partial pressure of carbon dioxide, and whether pressure-regulated volume control PRVC ventilation reduces these measurements. The study also investigates if intracranial pressure can be quickly assessed by monitoring the optic nerve sheath diameter ONSD. Participants are randomly assigned to one of three groups receiving different ventilation modes during surgery pressure control PC, volume control VC, or pressure-regulated volume control PRVC. Each group uses specific settings tailored to maintain proper oxygen levels and breathing parameters, including tidal volume based on ideal body weight, positive end-expiratory pressure, and respiratory rate. The study compares respiratory mechanics, carbon dioxide levels, and optic nerve sheath diameter among the groups. During the study, researchers monitor several outcomes including ONSD, carbon dioxide partial pressure, mean and peak airway pressures, esophageal pressure, tidal volume, mean arterial pressure, and heart rate over one year. Participants undergo these assessments throughout the trial to evaluate the impact of the ventilation modes on breathing and intracranial pressure. The study involves follow-up and data collection to understand how these ventilation techniques perform in bariatric surgery patients.

Effects of Different Anesthesia Machine Modalities on Bariatric Surgery Patients: a Prospective Randomized Controlled Study