Actively Recruiting

Age: 2Years - 12Years
All Genders
Healthy Volunteers
ID07323420

Effects of Different Inspiratory:Expiratory Ratios on Respiratory Function and Recovery in Pediatric Dental Procedures Under General Anesthesia

Led by Kırıkkale University · Updated on 2026-04-09

75

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of different inspiratory to expiratory (I:E) ratios during mechanical ventilation in children aged 2 to 12 years undergoing dental procedures under general anesthesia. This observational study compares the routine I:E ratio of 1:2 with a 1:3 ratio, aiming to see how these settings affect respiratory function and recovery quality during emergence from anesthesia. The goal is to find the best ventilation strategy to improve safety and comfort for pediatric patients during this process. All participants will receive standard anesthesia and dental care without any additional interventions. The study groups include children who emerge from anesthesia earlier than planned without preparation, those ventilated with an I:E ratio of 1:2, and those ventilated with an I:E ratio of 1:3 during the last phase of the procedure. The I:E ratio is adjusted 20-30 minutes before the end of surgery to help transition to spontaneous breathing. Throughout the study, vital signs and respiratory parameters such as heart rate, blood pressure, oxygen saturation, carbon dioxide levels, respiratory rate, and airway pressure will be monitored. Researchers will assess respiratory quality after extubation using a non-invasive scoring system and track recovery outcomes including physical responses, airway complications, anxiety, delirium levels, and discharge times. All data are recorded without altering routine clinical care, and the total follow-up covers emergence and recovery periods.

CONDITIONS

Brief Title

Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients

Who Can Participate

Age: 2Years - 12Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pediatric patients scheduled for dental procedures under general anesthesia at our faculty
  • American Society of Anesthesiologists (ASA) Physical Status I or II
  • Age between 2 and 12 years
  • Written informed consent obtained from parents or legal guardians
Not Eligible

You will not qualify if you...

  • Patients whose parents or legal guardians decline participation
  • Presence of adenoid hypertrophy greater than 30%
  • Macroglossia or retrognathia
  • Severe obesity or developmental delay
  • History of delayed emergence from anesthesia
  • ASA Physical Status III or higher
  • Anesthesia duration less than 1 hour or more than 3 hours
  • Patients with difficult airway management or ventilation
  • Known pulmonary or airway diseases or anomalies
  • Use of pharmacological agents that may affect spontaneous respiratory quality
  • Presence of neuromuscular disorders affecting respiratory function
  • Age below 2 years or above 12 years
  • Administration of medications intraoperatively or preoperatively that may influence respiratory dynamics during emergence (e.g., atropine, lidocaine, steroids)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Procedure day and up to 2 hours post-procedure

Participants undergoing routine dental procedures under general anesthesia are observed using a non-invasive scoring system during emergence from anesthesia to assess respiratory quality and recovery outcomes without additional interventions.

1 visit during the procedure with observation continuing up to 2 hours post-procedure

Trial Site Locations

Total: 1 location

1

Kırıkkale University, Faculty of Dentistry

Kirikkale, Turkey (Türkiye)

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Research Team

G

Gözde Nur Erkan Assisstant Professor

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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