Actively Recruiting
The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study
Led by Theodor Bilharz Research Institute · Updated on 2024-05-16
52
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Propofol is currently the most common drug used but has drawbacks like narrow therapeutic window and potential complications. Dexmedetomidine is an attractive alternative due to its unique properties like minimal respiratory depression. Studies are ongoing to find the optimal use of dexmedetomidine for these procedures. A combination of propofol and dexmedetomidine might be ideal, but the best balance between the two drugs needs further investigation.
CONDITIONS
Official Title
The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 65 years
- Both sexes
- American Society of Anesthesiologists (ASA) physical status I or II
- Body Mass Index (BMI) less than 35
You will not qualify if you...
- Patients who refuse to participate
- ASA physical status III or IV
- BMI greater than 35
- Patients at high risk of aspiration, such as those with gastric outlet obstruction
- Allergy to any study medications
- Diabetes
- Use of cardioactive drugs such as beta blockers, calcium channel blockers, or inhaled B2 bronchodilators
- Presence of pacemakers or heart rate below 50 beats per minute
- Pregnant women
- Habitual drug abusers
- Patients who required intubation during the procedure
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Theodor Bilharz Research Institute
Cairo, Giza Governorate, Egypt, 12411
Actively Recruiting
Research Team
S
Sameh M. Elaidy, Msc.
CONTACT
N
Nabawya Kamel, Proffessor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
4
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