Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT07184892

Effects of Different Modes of Action Observation Therapy on Swallowing Function After Stroke: a Study Based on fNIRS

Led by Qilu Hospital of Shandong University · Updated on 2025-09-22

90

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Dysphagia is one of the most common symptoms of stroke patients, which seriously affects the quality of life of patients and delays the progress of rehabilitation. At present, the commonly used clinical swallowing treatment methods can achieve certain therapeutic effects, but the treatment effect of some patients is still not ideal. Therefore, we need to explore more and more effective treatment methods to improve the swallowing function of patients. Action observation therapy, which was developed based on the mirror neuron theory, has been widely used in the rehabilitation of limb motor function, and its therapeutic effect has been verified by a large number of clinical trials. There are few clinical studies on action observation therapy in swallowing function rehabilitation, and most of the current studies use swallowing videos to allow patients to observe actions, and then guide patients to imitate actions. Some studies have found that oral mirror neurons can be formed in the context of familiar environment, people and emotional communication. Therefore, this study proposes a new mode of action observation therapy for dysphagia, that is, to observe the real swallowing movement in actual daily life, in order to better improve the swallowing function of stroke patients with dysphagia. This study was a single-center, assessor-blinded, randomized controlled study. After enrollment, all patients received swallowing assessment, including scale assessment (WST, FOIS, SSA, BMI, SWAL-QOL, VAS satisfaction survey, KVIQ motor imagery assessment, total oral intake/eating time), neck ultrasound and FNIRS brain function assessment. According to the random number table method, the patients were divided into three groups, A: control group, B: video swallowing movement observation therapy group, C: daily actual swallowing movement observation therapy group. All three groups were given routine swallowing function training. In group B, action observation therapy with video was added, that is, watching a video of swallowing action with sound, and then performing simulated swallowing action. Group C added the actual swallowing movement observation therapy in daily life, that is, in actual daily life, to observe the real eating and swallowing movement of relatives, and then imitate the swallowing movement. The training sessions were 30min each time, once a day, 5 days a week, for a total of 3 weeks. After the treatment, the scale assessment, neck ultrasound and FNIRS brain function assessment were performed again.

CONDITIONS

Official Title

Effects of Different Modes of Action Observation Therapy on Swallowing Function After Stroke: a Study Based on fNIRS

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with stroke according to national cerebrovascular disease criteria
  • Dysphagia confirmed by water swallowing test
  • First stroke onset within 6 months, condition stable
  • Mini-mental state exam score: literacy 17, primary education 20, secondary education 24; able to understand and cooperate
  • Able to maintain sitting position for 30 minutes
  • Aged 18 to 80 years
  • Patient and family informed and consented, able to cooperate with therapy
Not Eligible

You will not qualify if you...

  • Swallowing problems caused by other reasons
  • Tumors or lesions in mouth or throat
  • Visual or hearing impairments
  • Agnosia, apraxia, or unilateral neglect
  • Severe cognitive impairment or mental instability preventing cooperation
  • Presence of ferromagnetic metals implanted or retained in the brain

AI-Screening

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Trial Site Locations

Total: 1 location

1

Qilu Hospital

Jinan, Shandong, China, 250000

Actively Recruiting

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Research Team

艳平 Yanping Ma

CONTACT

Y

Yonghui Wang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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