Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT04307238

Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity

Led by Medical University of Vienna · Updated on 2025-07-04

108

Participants Needed

1

Research Sites

313 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Objective: To compare the effects of volatile and intravenous anesthetics on pupillary function after general anesthesia using a portable infrared pupillometer. Design: A monocentric, prospective, double blinded randomized study. Patients: Patients who require elective Ear, Nose and Throat (ENT) surgery under general anesthesia. Interventions: Patients undergoing elective ENT surgery will be assigned to intravenous versus inhalative anesthesia and pupillometric parameters monitored postoperative, using an infrared pupillometer. Outcomes measures: Reported pupillometric parameters after intravenous and inhalative anesthesia. The purpose of this study is to compare general anesthesia techniques (volatile, intravenous) on postoperative changes in pupillary reactivity by using infrared pupillometry.

CONDITIONS

Official Title

Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 60 18 and 60 99 years
  • ASA physical status I or II
  • Patients scheduled for elective Ear, Nose, and Throat (ENT) surgery under general anesthesia
Not Eligible

You will not qualify if you...

  • Patients younger than 18 or older than 99 years
  • Use of antidepressants, tranquilizers, or psychotropic medications
  • History of mental illness, neurosurgery, neurological or psychiatric disease
  • Presence of ophthalmologic disease
  • Preexisting cognitive impairment
  • Drug dependence or alcoholism
  • Inability to follow procedures
  • Presence of implanted electronic medical devices

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Medical University Vienna

Vienna, State of Vienna, Austria, 1090

Actively Recruiting

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Research Team

M

Marita Windpassinger, MD

CONTACT

O

Olga Plattner, Prof.MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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