Actively Recruiting
Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease
Led by University of British Columbia · Updated on 2025-01-15
15
Participants Needed
2
Research Sites
125 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Exercise training as part of a structured pulmonary rehabilitation program is a key factor in improving quality of life and symptoms in people with interstitial lung disease (ILD). Optimal methods of exercise training are yet to be explored in ILD. Drinking beetroot juice, which is rich in nitrate, has been shown to improve exercise performance in a variety of groups, but its effects in ILD have not been tested. The purpose of this study is to determine if drinking nitrate-rich beetroot juice can improve exercise performance compared to drinking nitrate-free beetroot juice in people with ILD.
CONDITIONS
Official Title
Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with idiopathic pulmonary fibrosis, fibrotic nonspecific interstitial pneumonia, chronic hypersensitivity pneumonitis, or unclassifiable ILD matching these diagnoses
- Presence of fibrosis on lung CT scan showing honeycombing, reticulation, or traction bronchiectasis
- Oxygen saturation of 92% or higher at rest on room air by pulse oximetry
- Clinically stable with no worsening symptoms for at least 6 weeks prior
- Able to read and write fluently in English
You will not qualify if you...
- Contraindications to exercise testing such as significant cardiovascular, musculoskeletal, or neurological disease
- Other major lung or systemic diseases that could reduce exercise capacity or oxygen levels
- Forced vital capacity (FVC) less than 50% predicted or diffusing capacity of the lungs for carbon monoxide (DLCO) less than 25%
- Use of prednisone over 10 mg daily for more than 2 weeks within 3 months before study start
- Presence of a cardiac pacemaker or any metal or electronic implants inside the body
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Providence Health Care - St. Paul's Hosptial
Vancouver, British Columbia, Canada, V6Z 1Y6
Actively Recruiting
2
Vancouver Coastal Health
Vancouver, Canada, V5Z 1M9
Actively Recruiting
Research Team
O
Olivia Ferguson, MSc
CONTACT
D
Dhillon Satvir, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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