Actively Recruiting
Effects of E-cigarette Use on Health
Led by University of Wisconsin, Madison · Updated on 2025-12-24
600
Participants Needed
1
Research Sites
233 weeks
Total Duration
On this page
Sponsors
U
University of Wisconsin, Madison
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown. This research proposal will quantify the effects of long-term ENDS use on validated and novel biomarkers of cardiovascular and pulmonary disease and how they are influenced by use heaviness, age, body weight, and co-use of other products. This study will produce the most informative evidence to date on how long-term ENDS use affects cardiovascular and pulmonary health.
CONDITIONS
Official Title
Effects of E-cigarette Use on Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 21 years of age or older
- Have vaped a nicotine e-cigarette product at least 2 days per week for most weeks for 12 months or more
- Plan to stay in the study area for at least 3 years
- Smoked 5 or fewer tobacco cigarettes in the past 6 months
- No serious cardiovascular, pulmonary, or other medical problems
- Not currently pregnant
- No plans to stop vaping
You will not qualify if you...
- Serious cardiovascular, pulmonary, or other medical problems such as moderate/severe aortic stenosis, class III or IV heart failure, blood pressure 160/100 mmHg or higher, interstitial lung disease, sarcoidosis, or Stage 3 or 4 cancer
- Use of combusted or vaped cannabis 3 or more days per week in the past 3 months
- Currently pregnant
- Unable to read and write English
- Incarceration
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UW Center for Tobacco Research and Intervention
Madison, Wisconsin, United States, 53711
Actively Recruiting
Research Team
J
James Stein, MD
CONTACT
T
Timothy Baker, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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