Actively Recruiting

Phase Not Applicable
Age: 2Months - 5Months
All Genders
NCT07201805

Effects of Early Physiotherapy on Motor Optimality Score in At-Risk of Infants

Led by Kahramanmaras Sutcu Imam University · Updated on 2025-10-01

50

Participants Needed

1

Research Sites

60 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Medical and technological advances in neonatal care have led to a decrease in neonatal mortality and an increase in the survival of very low birth weight infants, leading to a global increase in the prevalence of cerebral palsy (CP), cardiorespiratory disorders, blindness, cognitive delays, and hearing impairments. Early diagnosis and intervention programs have been established to meet the developmental needs of these at-risk infants in the neonatal intensive care unit (NICU). The goal of these programs is to facilitate the development of at-risk infants and normalize their motor, cognitive, and sensory development.Research remains unclear about which interventions are more effective when implemented. It is known that early intervention improves motor development in these infants, and that programs that include parents have more positive long-term outcomes for the cognitive and language development of at-risk infants.General Movements (GMs) are spontaneous movements that occur from the fetal period to 18 weeks postterm. Prechtl's General Movements Assessment (GMA) is a reliable tool for functional assessment of the young central nervous system.The assessment of motor repertoire (via the motor optimality score, MOS) describes the quality and quantity of the concurrent motor repertoire recorded during the GM assessment.The revised motor optimality score (MOS-R) has the potential to increase the prediction of adverse neurodevelopmental outcomes. It is noteworthy that the literature contains limited studies examining the effect of early physiotherapy applied to at-risk infants after NICU discharge on MOS-R. Therefore, the aim of this planned study was to investigate the effect of early family collaborative physiotherapy approaches applied to at-risk infants after NICU discharge on GMs MOS-R. Another aim was to determine the effect of early physiotherapy on neurological examination, cognitive, and language development in infants at 3 and 6 months of age and to compare them with similar peers receiving a routine treatment protocol.

CONDITIONS

Official Title

Effects of Early Physiotherapy on Motor Optimality Score in At-Risk of Infants

Who Can Participate

Age: 2Months - 5Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Infants diagnosed with periventricular hemorrhage, intracranial hemorrhage, cystic periventricular leukomalacia, hypoxic ischemic encephalopathy, kernicterus, perinatal asphyxia, neonatal sepsis, necrotizing enterocolitis, retinopathy of prematurity, respiratory distress syndrome, or bronchopulmonary dysplasia, and those receiving oxygen or mechanical ventilation support
  • Infants with a 5-minute Apgar score less than 3, born before 37 weeks' gestation, birth weight under 1500 grams, or prematurity due to multiple births
  • Infants with a corrected age of 2 to 4 months
Not Eligible

You will not qualify if you...

  • Infants with congenital malformations such as spina bifida, congenital muscular torticollis, or arthrogryposis multiplex congenita
  • Infants diagnosed with metabolic or genetic diseases including Down syndrome, spinal muscular atrophy, or Duchenne muscular dystrophy

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Kahramanmaraş Sütçü imam University

Kahramanmaraş, Onikişubet, Turkey (Türkiye), 46100

Actively Recruiting

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Research Team

H

hatice adıgüzel tat, Associate Proffessor

CONTACT

H

hatice Adiguzel tat, Associate Proffessor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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