Actively Recruiting
The Effects of Endotracheal Suctioning on Pain and Serum Markers
Led by Loma Linda University · Updated on 2025-05-21
110
Participants Needed
1
Research Sites
60 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but this procedure may be uncomfortable and cause stress. The main questions this study aims to answer are: Does ETT suctioning raise pain levels as measured by the Critical-Care Pain Observation Tool (CPOT)? Does ETT suctioning increase certain chemicals in the blood (hypoxanthine, xanthine, and uric acid) that show stress and lack of oxygen in the body? Researchers will compare patients who have ETT suctioning (intervention group) with those who do not have suctioning during the study period (control group) to see if there are differences in pain and blood markers of stress. Participants will: Have pain measured before and after suctioning using the CPOT. Have blood samples taken from an existing line at three time points: 5 minutes before, 5 minutes after, and 30 minutes after suctioning. Provide demographic information (like age, gender, and diagnosis) from medical records. This research will help improve how pain is managed for ICU patients who cannot speak for themselves, potentially leading to better pain relief methods in the future.
CONDITIONS
Official Title
The Effects of Endotracheal Suctioning on Pain and Serum Markers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (aged 18 years and older)
- Current diagnosis of flu, pneumonia, COVID, or sepsis
- Intubated and receiving mechanical ventilation
- Have arterial lines placed
- Require endotracheal suctioning as part of their care
You will not qualify if you...
- Patients receiving neuromuscular blocking agents
- Contraindications for blood draws such as hemoglobin levels below 8.0 g/dL
- Jehovah's Witness
AI-Screening
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Trial Site Locations
Total: 1 location
1
Loma Linda University Medical Center Troesh Medical Campus
Loma Linda, California, United States, 92354
Actively Recruiting
Research Team
B
Briana Carr, PhD(c), BSN, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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