Study of Pain and Stress Markers During Endotracheal Suctioning in Intubated Adults in the ICU

What this Trial Is About

This research aims to understand if endotracheal tube ETT suctioning causes increased pain and stress in adult ICU patients who are intubated and on ventilators. The study focuses on measuring changes in pain using the Critical-Care Pain Observation Tool CPOT and levels of blood chemicals that indicate stress and low oxygen in the body. Researchers compare patients who receive ETT suctioning with those who do not during the study period to see if there are differences in these measures. Participants will either receive ETT suctioning as part of their normal care or will not undergo suctioning during the observation period. Pain levels will be recorded before and after suctioning, and blood samples will be taken from existing arterial lines at three specific times 5 minutes before suctioning, 5 minutes after, and 30 minutes after. This procedure helps assess the impact of suctioning on pain and markers of stress. During the study, participants pain will be closely monitored using the CPOT scale, and blood samples will be analyzed for markers of hypoxia and oxidative stress such as hypoxanthine. Demographic and medical information will be collected from medical records. The study helps improve pain management approaches for ICU patients who cannot communicate their discomfort, with the total participation lasting until the primary completion date in late 2026.

The Effects of Endotracheal Suctioning on Pain and Serum Markers