Actively Recruiting
Opioid Usage and Patient Reported Outcome Comparison Following Erector Spinae Plane Block or Subcutaneous Anesthetic in Spinal Fusion Procedures
Led by University of Massachusetts, Worcester · Updated on 2026-03-16
66
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how different methods of injecting local anesthesia affect pain and opioid use after lumbar fusion surgery. The trial compares subcutaneous anesthesia, which involves injecting anesthesia under the skin near the surgical incision, to the erector spinae plane block (ESPB), where anesthesia is injected along the back muscles and bones using fluoroscopy for guidance. The study will use patient-reported outcomes and track opioid use to see if ESPB leads to less pain and lower opioid consumption compared to subcutaneous injections. Participants will receive either an ESPB injection before surgery while under general anesthesia or a subcutaneous anesthesia injection after surgery but still under general anesthesia. Both injections contain saline, liposomal bupivacaine, and bupivacaine, with the ESPB targeting the erector spinae fascial plane at the surgical levels and the subcutaneous injection around the incision site. During the study, patients will be monitored for pain, disability, and opioid use at specific times after surgery. Outcomes include the MOS 36 Item Short Form Health Status Survey and the Oswestry Disability Index at three months, as well as opioid usage in the two weeks following surgery. The study is randomized and double-blinded to fairly compare the two anesthesia methods, with follow-up assessments to evaluate patient recovery and opioid consumption.
CONDITIONS
Brief Title
Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent form approved by the Institutional Review Board at UMMHC
- At least 18 years of age
- Skeletally mature (over the age of 18)
- Scheduled for a one or two level lumbar spinal fusion
You will not qualify if you...
- Unable to consent for themselves
- Pregnant women
- Non-English speaking subjects
- Prisoners
- Spinal fusion procedures for fracture, tumor, or infection
- Used more than 150 morphine milligram equivalents of opioids in the month prior to surgery
- Body mass index (BMI) of 40 or greater
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 2 weeks
Participants receive either an erector spinae plane block before surgery or a subcutaneous anesthesia injection after surgery to help reduce postoperative pain.
1 surgical procedure visit and hospital stay
Duration - Up to 3 months
Participants are monitored for postoperative opioid usage and recovery through patient-reported outcomes and health status surveys.
Follow-up visits for assessments over 3 months
Trial Site Locations
Total: 1 location
1
UMass Chan Medical School/UMass Memorial Medical Center
Worcester, Massachusetts, United States, 01655
Actively Recruiting
Research Team
M
Michael P Stauff, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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