Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06528288

Opioid Usage and Patient Reported Outcome Comparison Following Erector Spinae Plane Block or Subcutaneous Anesthetic in Spinal Fusion Procedures

Led by University of Massachusetts, Worcester · Updated on 2026-03-16

66

Participants Needed

1

Research Sites

25 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating how different methods of injecting local anesthesia affect pain and opioid use after lumbar fusion surgery. The trial compares subcutaneous anesthesia, which involves injecting anesthesia under the skin near the surgical incision, to the erector spinae plane block (ESPB), where anesthesia is injected along the back muscles and bones using fluoroscopy for guidance. The study will use patient-reported outcomes and track opioid use to see if ESPB leads to less pain and lower opioid consumption compared to subcutaneous injections. Participants will receive either an ESPB injection before surgery while under general anesthesia or a subcutaneous anesthesia injection after surgery but still under general anesthesia. Both injections contain saline, liposomal bupivacaine, and bupivacaine, with the ESPB targeting the erector spinae fascial plane at the surgical levels and the subcutaneous injection around the incision site. During the study, patients will be monitored for pain, disability, and opioid use at specific times after surgery. Outcomes include the MOS 36 Item Short Form Health Status Survey and the Oswestry Disability Index at three months, as well as opioid usage in the two weeks following surgery. The study is randomized and double-blinded to fairly compare the two anesthesia methods, with follow-up assessments to evaluate patient recovery and opioid consumption.

CONDITIONS

Brief Title

Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent form approved by the Institutional Review Board at UMMHC
  • At least 18 years of age
  • Skeletally mature (over the age of 18)
  • Scheduled for a one or two level lumbar spinal fusion
Not Eligible

You will not qualify if you...

  • Unable to consent for themselves
  • Pregnant women
  • Non-English speaking subjects
  • Prisoners
  • Spinal fusion procedures for fracture, tumor, or infection
  • Used more than 150 morphine milligram equivalents of opioids in the month prior to surgery
  • Body mass index (BMI) of 40 or greater

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 2 weeks

Participants receive either an erector spinae plane block before surgery or a subcutaneous anesthesia injection after surgery to help reduce postoperative pain.

1 surgical procedure visit and hospital stay

Follow-up

Duration - Up to 3 months

Participants are monitored for postoperative opioid usage and recovery through patient-reported outcomes and health status surveys.

Follow-up visits for assessments over 3 months

Trial Site Locations

Total: 1 location

1

UMass Chan Medical School/UMass Memorial Medical Center

Worcester, Massachusetts, United States, 01655

Actively Recruiting

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Research Team

M

Michael P Stauff, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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