Actively Recruiting
Effects of Fibres Combined With Probiotics on Uric Acid in an ex Vivo Fermentation Model
Led by Örebro University, Sweden · Updated on 2025-08-12
15
Participants Needed
1
Research Sites
181 weeks
Total Duration
On this page
Sponsors
Ö
Örebro University, Sweden
Lead Sponsor
U
University of Copenhagen
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this study, we will collect faecal samples from individuals with hyperuricaemia (assessed by blood test) and perform in vitro faecal fermentation studies to assess how probiotics in combination with fibres affect urate metabolism in these faecal samples.
CONDITIONS
Official Title
Effects of Fibres Combined With Probiotics on Uric Acid in an ex Vivo Fermentation Model
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent before any study procedures
- Age between 18 and 80 years
- Body Mass Index (BMI) between 18.5 and 35 kg/m2
- Blood uric acid level above 0.36 mmol/L (6 mg/dl)
- Willing to avoid regular use of probiotic supplements or probiotic-containing foods until stool collection
- Willing to avoid regular use of supplements or medications that affect gut function or inflammation until stool collection
You will not qualify if you...
- Diagnosed with type 1 or type 2 diabetes
- Diagnosed with inflammatory bowel disease (IBD)
- Currently diagnosed with psychiatric diseases or syndromes
- Currently diagnosed with neurodegenerative diseases
- Currently pregnant or breastfeeding
- History of complicated gastrointestinal surgery
- Used systemic antibiotics or steroid medications within the last 4 months
- Regular use of non-steroidal anti-inflammatory drugs (NSAIDs) in the last 2 months
- Taken any NSAIDs within 3 days before sample collection
- Used probiotic supplements within 4 weeks prior to study start
- Any condition or medication use that could affect study results, as judged by the principal investigator
- Starting any new medication or treatment that might impact participation or analysis after study inclusion and before stool collection
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Örebro University
Örebro, Sweden
Actively Recruiting
Research Team
J
Julia König, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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