Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT05939674

Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam

Led by Pusan National University Yangsan Hospital · Updated on 2025-09-12

24

Participants Needed

1

Research Sites

140 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Remimazolam is a medication that has the advantage of a short half-life and reversibility with flumazenil. In clinical situations, the use of flumazenil for the reversal of sedation is common, but there is no precise indication for its administration. In this study, we aim to investigate the necessity of routine flumazenil use after administering remimazolam for intravenous anesthesia.

CONDITIONS

Official Title

Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 65 years old scheduled for hip joint surgery
Not Eligible

You will not qualify if you...

  • Patients with impaired consciousness or delirium before surgery
  • Patients who are hemodynamically unstable before surgery
  • Patients with a history of neurological or neuromuscular disorders or use of medications that affect neurological or neuromuscular function
  • Patients who have taken sedatives (anti-anxiety medications, antipsychotics, antidepressants, sleep aids) within the past 24 hours
  • Patients with known allergy to benzodiazepine, flumazenil
  • Patients with galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption
  • Patients with hypersensitivity to Dextran40
  • Patients who have been taking benzodiazepine for long term
  • Patients with end stage renal disease requiring hemodialysis
  • Patients with history of acute angle glaucoma
  • Patients with alcohol or substance dependence
  • ASA classification 4 or 5

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Pusan National University Yangsan Hospital

Yangsan, Gyeongsangnam-do, South Korea, 50612

Actively Recruiting

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Research Team

J

Jaesang BAE, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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