Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
Healthy Volunteers
NCT06343259

The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury

Led by Sisli Hamidiye Etfal Training and Research Hospital · Updated on 2024-07-23

100

Participants Needed

1

Research Sites

19 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery. Cardiovascular events are a leading cause of mortality and morbidity following non-cardiac surgery, with myocardial injury after non-cardiac surgery (MINS) being a significant concern. MINS, characterized by asymptomatic elevation of troponin levels without accompanying ECG findings, is closely associated with postoperative mortality. With the increasing prevalence of comorbidities in the elderly population and the rising frequency of non-cardiac surgeries in this demographic, understanding the effects of different anesthesia types on postoperative myocardial injury is crucial.

CONDITIONS

Official Title

The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury

Who Can Participate

Age: 65Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 65 years or older
  • Patients undergoing hip surgery
  • Patients classified as ASA II-III
Not Eligible

You will not qualify if you...

  • Patients diagnosed with sepsis, pulmonary embolism, decompensated heart failure, or chronic kidney failure
  • Patients who had cardioversion or myocardial infarction within the last 6 months
  • Patients with surgery in the last month
  • Patients who required intubation in the intensive care unit
  • Patients with baseline high-sensitivity Troponin T value exceeding 20 ng/L
  • Patients with postoperative peak high-sensitivity Troponin T value higher than baseline

AI-Screening

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Trial Site Locations

Total: 1 location

1

Sisli Hamidiye Etfal Training and Research Hospital

Istanbul, Turkey (Türkiye), 34396

Actively Recruiting

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Research Team

M

Mustafa Bilgehan AYIK

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury | DecenTrialz