Actively Recruiting
Effects of Goji vs. Fiber on Macular Degeneration
Led by University of California, Davis · Updated on 2025-06-24
60
Participants Needed
1
Research Sites
165 weeks
Total Duration
On this page
Sponsors
U
University of California, Davis
Lead Sponsor
U
United States Department of Agriculture (USDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this project is to conduct a clinical trial in 60 participants ranging from age 65-95 who are at risk for age-related macular degeneration (AMD). The study will evaluate the effects of 14g of goji berry intake or an equivalent amount and type of fiber, five days a week for six months, on visual health, gut microbiome profiles, skin carotenoid measures, and lipoprotein profiles.
CONDITIONS
Official Title
Effects of Goji vs. Fiber on Macular Degeneration
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Family history of AMD
- Hyperlipidemia or managed diabetes
- Age between 65 and 95 years
You will not qualify if you...
- Allergy to goji berries or any ingredients in the fiber supplements (wheat, corn, oats, soy, natural orange flavor, xylitol, annatto, pectin, or other food ingredients)
- Consumption of more than 2 alcoholic drinks per day
- Signs of substance or alcohol abuse
- Current or planned use of blood thinners (e.g., Coumadin, Warfarin) during the study
- Use of multivitamins or supplements containing lutein or zeaxanthin unless stopped at least 6 months prior
- New medications started within the past 6 months or planned changes within the next 6 months
- Planned international travel during the study
- Consuming more than 3 servings per day of certain vegetables (spinach, kale, lettuce, orange bell peppers, corn, parsley, squash, broccoli, pumpkin, edamame)
- Regularly consuming more than 3 eggs per day
- Participation in another interventional research study
- Diagnosis of inflammatory bowel disease, irritable bowel syndrome, other gastrointestinal disorders, undergoing cancer therapy, immunocompromised, or other conditions contraindicating lutein, zeaxanthin, or fiber supplementation
- Any physical condition preventing study procedures
- Medical or psychiatric conditions that could affect study results or participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UC Davis Eye Center, Tschannen Eye Institute
Sacramento, California, United States, 95817
Actively Recruiting
Research Team
D
Denise Macias, CCRP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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