Actively Recruiting
Effects of Grape Consumption on the Immune-Gut Axis in Obesity
Led by University of Missouri-Columbia · Updated on 2025-12-30
50
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
Sponsors
U
University of Missouri-Columbia
Lead Sponsor
C
California Table Grape Commission
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is investigating the benefits of whole freeze-dried grape powder consumption on the immune-gut axis in adults with obesity.
CONDITIONS
Official Title
Effects of Grape Consumption on the Immune-Gut Axis in Obesity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 30 and 45 years
- Obesity with a BMI of 30 to 45 kg/m2
- Willingness to consume study foods
- Consistent diet and physical activity patterns for at least 4 weeks
- Stable body weight with less than 5 kg change in the last 3 months
- Non-smoker for at least 1 year
- Not currently following an extremely healthy diet
You will not qualify if you...
- Allergy to study foods
- Regular consumption of grapes or grape-derived products
- Gastrointestinal disease or history of bariatric surgery
- Uncontrolled hypertension with blood pressure over 180/110
- Diagnosis of diabetes
- Clinical depression
- Use of illicit drugs
- History of alcohol or drug abuse
- Recent use of medications affecting immune function, such as corticosteroids
- Recent use of antibiotics, prebiotics, probiotics, symbiotics, or dietary supplements with fiber or phytochemicals
- Pregnant or breastfeeding
- HIV positive
- Recent start of medications affecting metabolism or appetite
- Current drug treatment for coronary artery disease, peripheral artery disease, congestive heart failure, or dyslipidemia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Missouri-Columbia
Columbia, Missouri, United States, 65211
Actively Recruiting
Research Team
J
Jaapna Dhillon PhD, PhD
CONTACT
C
Caitlyn Winn, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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