Actively Recruiting
The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health
Led by Penn State University · Updated on 2026-02-02
52
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
Sponsors
P
Penn State University
Lead Sponsor
C
Cotton Incorporated
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will examine the effect of a healthy diet containing cottonseed oil compared to healthy diets containing other commonly consumed plant oils on biomarkers of heart and metabolic health after 4 weeks.
CONDITIONS
Official Title
The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- LDL-C 65100 mg/dL and 64190 mg/dL
- BMI of 25-40 kg/m2
- Blood pressure <140/90 mmHg
- Fasting blood glucose <126 mg/dL
- Fasting triglycerides <350 mg/dL
- 6410% change in body weight for 6 months prior to enrollment
You will not qualify if you...
- Type 1 or type 2 diabetes or fasting blood glucose 65126 mg/dL
- Prescription of anti-hypertensive, lipid lowering or glucose lowering drugs
- Intake of supplements that affect the outcomes of interest and unwilling to cease during the study period
- Diagnosed liver, kidney, or autoimmune disease
- Prior cardiovascular event (e.g., stroke, heart attack)
- Current pregnancy or intention of pregnancy within the next 6 months
- Lactation within prior 6 months
- Follows a vegetarian or vegan diet
- Food allergies/intolerance/sensitives/dislikes of foods included in the study menu
- Antibiotic use within the prior 1 month
- Oral steroid use within the prior 1 month
- Use of tobacco or nicotine containing products with in the past 6 months
- Cancer any site within the past 10 years (eligible if 6510 years without recurrence) or non-melanoma skin cancer with in the past 5 years (eligible if 655 years without recurrence)
- Participation in another clinical trial within 30 days of baseline
- Currently following a restricted or weight loss diet
- Prior bariatric surgery
- Intake of >14 alcoholic drinks/week and/or lack of willingness to consume a maximum of two standard drinks per week while enrolled in the study and/or not willing to avoid alcohol consumption for 48 hour prior to test visits
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Pennylvania State University
University Park, Pennsylvania, United States, 16802
Actively Recruiting
Research Team
K
Kristina Petersen, PhD
CONTACT
S
Stacey Meily
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
3
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