Actively Recruiting
The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms
Led by University of Reading · Updated on 2026-04-28
44
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
Sponsors
U
University of Reading
Lead Sponsor
E
eBeauty Ltd Innopure, Regus House, Cardiff Gate Business Park, Malthouse Avenue, Cardiff, CF23 8RU
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial investigates the effects of Vitamin B6 supplementation on neural inhibition using electroencephalography (EEG), in relation to depression and anxiety symptoms in participants from the general population with a relatively high level of symptoms at baseline. Researchers will compare a placebo group to high-dose Vitamin B6 to test the hypothesis that Vitamin B6 moves the excitation/inhibition balance towards inhibition.
CONDITIONS
Official Title
The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years of age and under 41
- Mild to moderate anxiety and/or depression
- Normal or corrected to normal vision
You will not qualify if you...
- Taking daily dietary supplement containing more than 2 mg Vitamin B6
- Taking medication that is a GABA agonist
- Currently pregnant
- Medical history of epilepsy
- Medical history of peripheral neuropathy
- Taking the antibiotic Seromycin
- History of brain injury or recent concussion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Harry Pitt Building
Reading, England, United Kingdom, RG6 6ES
Actively Recruiting
Research Team
A
Alex Cameron
CONTACT
D
David T Field
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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