Actively Recruiting

Phase Not Applicable
Age: 60Years - 74Years
FEMALE
Healthy Volunteers
NCT06888544

Effects of High-Intensity Interval Training on Bone Health in Hong Kong Older Women

Led by Hong Kong Baptist University · Updated on 2025-03-21

48

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Osteoporosis is an age-related disease, characterized by a decreased bone mass and an increased risk of fragility fractures. Osteoporosis leads to increasing mortality, disabilities, morbidity of chronic pain, and the cost of health and social care, as well as decreasing the quality of life from reduced independence and hindered physical, mental, and social well-being. A recent review and meta-analysis, investigating the association between physical activity and osteoporosis prevention in elderly people, indicated that the traditional exercise interventions (i.e., resistance training) were undertaken for 60+ mins, 2-3 times/week for 7+ months. However, participation rates remain low in these exercise programs among older adults, in part due to a need for specialized equipment and correct techniques to prevent injury. In addition, low motivation and associated compliance with such conventional exercise is problematic among older adults. Considering there is little evidence of HIIT benefits related to older women with osteopenia, the current study aims to evaluate the effectiveness of a 24-week HIIT intervention on bone mineral density, bone turnover markers and other health-related outcomes among Hong Kong Chinese older women.

CONDITIONS

Official Title

Effects of High-Intensity Interval Training on Bone Health in Hong Kong Older Women

Who Can Participate

Age: 60Years - 74Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female aged 60 to 74 years at the start of the study
  • Diagnosed with osteopenia by DXA scan with bone mineral density T-score between -1 and -2.5 at femoral neck, total hip, or lumbar spine
  • Passed PAR-Q plus screening or have physician approval to participate in high-intensity exercise
  • Have aerobic fitness above average on a 2-minute stepping test
  • No physical mobility restrictions
  • No cognitive impairment (score 24 or above on Chinese Mini-Mental Status Examination)
  • No previous significant experience with high-intensity interval training
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Severe chronic diseases that limit ability to perform high-intensity exercise
  • Cognitive impairment as diagnosed by specialists
  • Medical conditions such as thyrotoxicosis, hyperparathyroidism, Paget's disease, renal disease, diabetes, knee or hip osteoarthritis
  • Use of medications affecting bone metabolism in the past 2 years (e.g., corticosteroids, estrogen, thyroxine, thiazide diuretics, antiretroviral agents)
  • Diagnosis of osteoporosis or osteoporotic fractures
  • Current smoker
  • Consume 3 or more units of alcohol daily

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Bliss District Elderly Community Centre

China, Hong Kong, China, 999077

Actively Recruiting

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Research Team

Y

Yanping Duan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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