Actively Recruiting
The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients
Led by SHUANG ZHENG JIA, PhD · Updated on 2025-12-05
50
Participants Needed
1
Research Sites
152 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this open-label randomized control trial is to study the effect of immunonutrition in locally advanced cervical cancer (LACC) with standard concurrent chemoradiotherapy. LACC patients undergoing radical synchronous chemoradiotherapy will be randomized into the experimental group receiving enteral immunonutrition therapy and the control group receiving standard enteral nutrition support.The main purpose it aims to answer are:1）Can immunonutrition therapy improve patients' dose-limiting toxicity(DLT) and DLT-free survival? 2）Can immunonutrition therapy improve patients' nutritional status and quality of life?
CONDITIONS
Official Title
The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years
- Confirmed diagnosis of cervical squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma
- Diagnosed with locally advanced cervical cancer by gynecological exam and imaging
- Currently undergoing concurrent chemoradiotherapy or radiotherapy
- Able to communicate clearly and answer questions
- Diagnosed with malnutrition based on GLIM criteria
You will not qualify if you...
- Previous neoadjuvant chemotherapy or immunotherapy before treatment
- Presence of other malignant tumors or history of cancer
- Special tumor types such as cervical small cell carcinoma or neuroendocrine tumors
- FIGO 2018 staging of IIIb
- Severe chronic diseases like heart failure class II-IV, severe liver damage, or severe kidney insufficiency
- ECOG performance status 2
- Other contraindications to concurrent chemoradiotherapy or radiotherapy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cancer Hospital, Chinese Academy of Medical Sciences
Beijing, China, 100021
Actively Recruiting
Research Team
S
SHUANGZHENG JIA, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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