Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation (ORIF): A Single Centre, Double Blinded, Randomised Control Trial

What this Trial Is About

Researchers are evaluating the safety and effectiveness of an intra-articular analgesic cocktail injection for patients who have undergone surgery to fix a fractured patella, the kneecap. The study aims to compare pain relief and functional recovery between patients who receive this injection during surgery and those who do not. Additionally, the study looks at whether this injection can reduce hospital stays and related complications, which could lower healthcare costs. This study is a single-center, double-blinded, randomized control trial where participants are assigned to one of two groups. One group receives an injection of a cocktail containing Ketorolac 15mg, Ropivacaine 1% 15ml, Normal Saline 35ml, Adrenaline 0.5ml, and Triamcinolone Acetonide 40mg directly into the surgical site after fracture fixation. The other group does not receive any injection. The total volume of the injected cocktail is about 50ml. The trial compares outcomes between these two groups. Participants will be monitored for pain using a Numerical Patient Reported Scale before surgery and during the first three days after surgery. Researchers will also assess knee movement, oral pain medication use over two weeks, and knee function scores at two weeks post-operation. Quality of recovery will be measured in the first three days after surgery. Secondary outcomes include length of hospital stay, time for bone healing seen in X-rays over about a year, and any complications. The study lasts for roughly one year for each participant, with ongoing safety and recovery assessments.

Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation