Actively Recruiting
Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults
Led by University of Arkansas · Updated on 2025-07-18
20
Participants Needed
1
Research Sites
115 weeks
Total Duration
On this page
Sponsors
U
University of Arkansas
Lead Sponsor
N
National Pork Board
Collaborating Sponsor
AI-Summary
What this Trial Is About
We will be directly comparing a high-quality protein diet composed primarily of lean pork loin (PORK) to a lower-quality plant-based protein diet (PLANT) in individuals with prediabetes on muscle and whole-body protein turnover and glucose regulation.
CONDITIONS
Official Title
Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males and females ages 40-65 years
- Body mass index 25 to 40 kg/m2 or body fat percentage 25% or higher in males or 36% or higher in females
- Able to provide informed consent
- COVID-19 negative or asymptomatic
- Willing to abstain from alcohol, marijuana, and CBD products during the 4-day meal period
- HbA1c between 5.7% and 6.4% or fasting glucose between 100 and 125 mg/dL
You will not qualify if you...
- Does not eat or will not eat animal protein sources
- Allergy to wheat, soy, or common plant-based protein ingredients
- Body mass index less than 25 kg/m2 or greater than 40 kg/m2
- Hemoglobin less than 10 g/dL at screening
- Platelet count less than 150,000/uL at screening
- History of chemotherapy or radiation therapy for cancer within 6 months prior to enrollment
- History of gastrointestinal bypass or reduction surgery
- Pregnant or lactating individuals
- History of chronic inflammatory diseases such as Lupus or Crohn's disease
- Currently receiving androgen or anabolic therapy
- Currently using prescription blood thinners
- Currently using corticosteroid medications
- Unable or unwilling to stop aspirin use for 7 days before Visit 3 and Visit 7
- Unwilling to avoid protein or amino acid supplements during participation
- Unwilling to fast overnight
- Unwilling to avoid alcohol, marijuana, and CBD products during the 4 study days
- On glucagon-like-peptide-1 receptor agonist medications for less than 1 month or with less than one injection every two weeks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
Actively Recruiting
Research Team
D
David Church, PhD
CONTACT
A
Amanda Gwin, PA-C
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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