Actively Recruiting
Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass
Led by China National Center for Cardiovascular Diseases · Updated on 2021-01-20
400
Participants Needed
1
Research Sites
348 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative atrial fibrillation.New-onset atrial fibrillation (NOAF) after coronary artery bypass graft is related to an increased short-term and long term risk of stroke and mortality.Marshall ligament amputation may reduce the occurence of atrial fibrillation. However, little is known whether this approach is justified during the coronary artery bypass graft.Therefore, this study aimed to investigate whether LAAO and Marshall ligament amputation during off-pump coronary artery bypass was associated with reduced risks of postoperative new-onset atrial fibrillation and stroke.
CONDITIONS
Official Title
Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing their first isolated off-pump coronary artery bypass surgery
You will not qualify if you...
- History or presence of atrial fibrillation before surgery
- Concurrent cardiac or non-cardiac surgery
- Conversion to on-pump bypass surgery during operation
- Emergency surgery
- Previous heart surgery
- Severe organ dysfunction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fuwai Hospital
Beijing, China
Actively Recruiting
Research Team
H
Hengchao Wu, doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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