Actively Recruiting
Effects of LH and FSH on Metabolic Regulation in Cumulus Cells
Led by Kaohsiung Veterans General Hospital. · Updated on 2025-01-31
60
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The combined use of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) has improved IVF pregnancy rates in infertile women aged 35-40, but its mechanisms remain unclear. This prospective study will examine how FSH and LH combined treatment affects cumulus cell energy metabolism. Sixty participants will be divided into two groups receiving either combined therapy or FSH alone. The study will analyze patient characteristics, infertility history, and compare mitochondrial function in cumulus cells to evaluate treatment effectiveness.
CONDITIONS
Official Title
Effects of LH and FSH on Metabolic Regulation in Cumulus Cells
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 35-40 years
- Body mass index (BMI) between 18 and 30 kg/m2
- Planning to undergo IVF cycles
You will not qualify if you...
- Primary ovarian insufficiency
- History of oophorectomy
- Receiving oocyte donation
- Chromosome anomaly
- Congenital uterine anomaly
- Severe intrauterine adhesion
- Malignancy
- Using hormone therapy or supplements in recent 3 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Kaohsiung Veterans General Hospital
Kaohsiung City, Taiwan, 81362
Actively Recruiting
Research Team
L
Li-Te Lin
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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