Actively Recruiting
Effects of Long-term Remote Ischemic Preconditioning on Clinical Outcome in Patients With Acute Myocardial Infarction
Led by Henan Institute of Cardiovascular Epidemiology · Updated on 2025-09-18
2146
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
At present, there are 290 million cardiovascular patients in China, including 11 million patients with coronary heart disease. Remote ischemic preconditioning(RIPC) may play an effective endogenous cardiac protection.This study will explore whether long-term use of RIPC in patients with AMI after PCI and non interventional therapy can reduce the incidence of major adverse cardiovascular cerebrovascular events(MACCE) and improve clinical outcomes and long-term prognosis.
CONDITIONS
Official Title
Effects of Long-term Remote Ischemic Preconditioning on Clinical Outcome in Patients With Acute Myocardial Infarction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with acute myocardial infarction according to the Global Unified Definition of the Fourth Myocardial Infarction
You will not qualify if you...
- Patients who cannot tolerate remote ischemic preconditioning (RIPC) or RIPerC
- Presence of aortic dissection, coronary artery aneurysm, coronary artery fistula, or other systemic organic diseases
- Severe hypertension with uncontrolled systolic blood pressure over 180 mmHg or diastolic blood pressure over 120 mmHg
- Severe liver dysfunction (bilirubin > 20 mmol/L, prothrombin time > 2.0 ratio)
- Severe renal insufficiency (glomerular filtration rate < 30 ml/min/1.73 m2)
- Current use of nicorandil or other drugs affecting microcirculation
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fuwai Central China Cardiovascular Hospital
Zhengzhou, Henan, China, 450000
Actively Recruiting
Research Team
M
Muwei LI
CONTACT
G
GUO QUAN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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