Comparing Low-Load Blood Flow Restriction Training and High-Load Training for Chronic Achilles Tendinopathy in Adults Aged 18 to 50
Led by University of Gran Rosario · Updated on 2024-12-06
52
Participants Needed
1
Research Sites
39 weeks
Total Duration
AI-Summary
What this Trial Is About
This research aims to evaluate the clinical effects of low load training with blood flow restriction BFR-LLT compared to high load training HLT in adults aged 18 to 50 years with chronic midportion Achilles tendinopathy MAT. MAT is a common overuse injury causing pain, limited function, and disruption of sports activities. While high load training is effective, it can be difficult for some people to tolerate. BFR-LLT may offer a lower intensity alternative, but its effects on tendon pathology have not yet been studied.
Participants will be randomly assigned to one of two groups the BFR-LLT group will use a pneumatic tourniquet system on the thigh while performing two calf-raise exercises at 20% of their one-repetition maximum 1RM, with progressive load increases every four weeks. The HLT group will perform the same exercises at 70% 1RM, also with progressive increases. Both groups will train three times a week for 12 weeks, completing sets and repetitions tailored to their assigned training load, with rest periods between sets and exercises.
Throughout the study, participants will undergo evaluations at baseline, 6 weeks, and 12 weeks to measure changes in pain intensity and function using the VISA-A questionnaire. Additional assessments at baseline and 12 weeks will include tendon thickness, cross-sectional area, neovascularization, single-leg vertical jump, and calf-raise endurance. All assessments will be conducted by a blinded physiotherapist. The total study participation will last 12 weeks with ongoing monitoring of tendon health and function.
CONDITIONS
Brief Title
Effects of Low-load Resistance Training With Blood Flow Restriction in Patients With Achilles Tendinopathy
Research Team
G
Gonzalo Elias, PT
L
Leonardo Intelangelo, MSc, PT
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Clinical diagnosis of unilateral midportion Achilles tendinopathy
Achilles tendon pain lasting more than 3 months
Age between 18 and 50 years, both genders
Able to read and speak Spanish to provide consent and follow instructions
Able to attend in-clinic treatments 2 to 3 times weekly for 12 weeks
You will not qualify if you...
History of ankle or foot surgery
Previous Achilles tendon rupture
Heel pain within the last 3 months
Presence of systemic disorders or diseases
History of deep venous thrombosis, hypertension, or blood clotting disorders
Body mass index greater than 30 kg/m2
Pregnancy
Use of drugs such as local steroid injections or systemic fluoroquinolones
Average pain less than 2 on the Numeric Pain Rating Scale
VISA-A score above 90%
Inability to perform any of the study exercises
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 12 weeks
Participants undergo a 12-week rehabilitation program involving three weekly training sessions of either low-load resistance training with blood flow restriction or high-load training to improve Achilles tendinopathy symptoms and function.
3 visits per week
Follow-up
Duration - 12 weeks
Participants are assessed for changes in pain, function, tendon thickness, cross-sectional area, neovascularization, calf-raise endurance, and jump height at 6 and 12 weeks during the treatment period.
Assessments at baseline, 6 weeks, and 12 weeks
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
Low-load blood flow restriction training induces similar morphological and mechanical Achilles tendon adaptations compared with high-load resistance training.
Christoph Centner, Benedikt Lauber, Olivier R Seynnes...