Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
All Genders
ID05241197

Effects of Low-load Resistance Training With Blood Flow Restriction in Patients With Achilles Tendinopathy

Led by University of Gran Rosario · Updated on 2024-12-06

52

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the clinical effects of low load training with blood flow restriction (BFR-LLT) compared to high load training (HLT) in adults aged 18 to 50 years with chronic midportion Achilles tendinopathy (MAT). MAT is a common overuse injury causing pain, limited function, and disruption of sports activities. While high load training is effective, it can be difficult for some people to tolerate. BFR-LLT may offer a lower intensity alternative, but its effects on tendon pathology have not yet been studied. Participants will be randomly assigned to one of two groups: the BFR-LLT group will use a pneumatic tourniquet system on the thigh while performing two calf-raise exercises at 20% of their one-repetition maximum (1RM), with progressive load increases every four weeks. The HLT group will perform the same exercises at 70% 1RM, also with progressive increases. Both groups will train three times a week for 12 weeks, completing sets and repetitions tailored to their assigned training load, with rest periods between sets and exercises. Throughout the study, participants will undergo evaluations at baseline, 6 weeks, and 12 weeks to measure changes in pain intensity and function using the VISA-A questionnaire. Additional assessments at baseline and 12 weeks will include tendon thickness, cross-sectional area, neovascularization, single-leg vertical jump, and calf-raise endurance. All assessments will be conducted by a blinded physiotherapist. The total study participation will last 12 weeks with ongoing monitoring of tendon health and function.

CONDITIONS

Brief Title

Effects of Low-load Resistance Training With Blood Flow Restriction in Patients With Achilles Tendinopathy

Who Can Participate

Age: 18Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of unilateral midportion Achilles tendinopathy
  • Achilles tendon pain lasting more than 3 months
  • Age between 18 and 50 years, both genders
  • Able to read and speak Spanish to provide consent and follow instructions
  • Able to attend in-clinic treatments 2 to 3 times weekly for 12 weeks
Not Eligible

You will not qualify if you...

  • History of ankle or foot surgery
  • Previous Achilles tendon rupture
  • Heel pain within the last 3 months
  • Presence of systemic disorders or diseases
  • History of deep venous thrombosis, hypertension, or blood clotting disorders
  • Body mass index greater than 30 kg/m2
  • Pregnancy
  • Use of drugs such as local steroid injections or systemic fluoroquinolones
  • Average pain less than 2 on the Numeric Pain Rating Scale
  • VISA-A score above 90%
  • Inability to perform any of the study exercises

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 12 weeks

Participants undergo a 12-week rehabilitation program involving three weekly training sessions of either low-load resistance training with blood flow restriction or high-load training to improve Achilles tendinopathy symptoms and function.

3 visits per week

Follow-up

Duration - 12 weeks

Participants are assessed for changes in pain, function, tendon thickness, cross-sectional area, neovascularization, calf-raise endurance, and jump height at 6 and 12 weeks during the treatment period.

Assessments at baseline, 6 weeks, and 12 weeks

Trial Site Locations

Total: 1 location

1

University of Gran Rosario

Rosario, Santa Fe Province, Argentina, 2000

Actively Recruiting

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Research Team

G

Gonzalo Elias, PT

L

Leonardo Intelangelo, MSc, PT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Low-load blood flow restriction training induces similar morphological and mechanical Achilles tendon adaptations compared with high-load resistance training.

Christoph Centner, Benedikt Lauber, Olivier R Seynnes...

https://pubmed.ncbi.nlm.nih.gov/31725362

Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial.

Rikke Beyer, Mads Kongsgaard, Birgitte Hougs Kjær...

https://pubmed.ncbi.nlm.nih.gov/26018970

Efficacy of heavy eccentric calf training for treating mid-portion Achilles tendinopathy: a systematic review and meta-analysis.

Myles Calder Murphy, Mervyn J Travers, Paola Chivers...

https://pubmed.ncbi.nlm.nih.gov/30636702