Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT07005193

Effects of LPG and Ventilation Interventions on Reducing HAP and Improving Cardiopulmonary Health

Led by Huazhong University of Science and Technology · Updated on 2026-03-17

1200

Participants Needed

3

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate the independent and synergistic effects of liquefied petroleum gas (LPG) substitution and improved ventilation on household air pollution (HAP) reduction and cardiopulmonary health. The main questions it aims to answer are: 1. Does LPG substitution or improved ventilation reduce HAP and improve cardiopulmonary health? 2. Would the combined intervention of LPG substitution and improved ventilation outperform single interventions? 3. What is the cost-effectiveness of such interventions, and are they sustainable? 4. Does the intervention reduce the incidence of cardiopulmonary clinical events? Participants will be randomized in 4 groups: A: Solid fuel + no ventilation facilities group (300 households): Continued use of solid fuels without installation of ventilation facilities and receipt of standardized health education. No LPG stoves or ventilation equipment will be provided during the intervention period. However, after the primary endpoint assessment at 12 months, all households in Group A will be provided with LPG stoves and ventilation facilities of equivalent specifications free of charge, along with health guidance. Phased cash compensation will be provided during the intervention period. B: Liquefied petroleum gas (LPG) + no ventilation facilities group (300 households): Provided with LPG stoves and instructed to use them during cooking, with regular LPG supply throughout the intervention period. Participants will also receive standardized health education. C: Solid fuel + ventilation facilities group (300 households): Continued use of solid fuels while being provided with ventilation facilities and instructed to use them during cooking. Electricity costs will be compensated during the intervention period. Participants will also receive standardized health education. D: LPG + ventilation facilities group (300 households): Provided with both LPG stoves and ventilation facilities and instructed to use both during cooking. Regular LPG supply and electricity cost compensation will be provided throughout the intervention period. Participants will also receive standardized health education.

CONDITIONS

Official Title

Effects of LPG and Ventilation Interventions on Reducing HAP and Improving Cardiopulmonary Health

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 to 75 years
  • Local permanent resident with no plans for long-term travel or relocation within one year
  • Kitchen suitable for ventilation facility installation
  • Responsible for daily cooking, cooking at least 5 times per week
  • Living in naturally ventilated, open villages with preference for detached houses at least 10 meters from neighboring kitchens
  • Elderly individuals aged 65 to 75 living with the primary participant
  • Children aged 3 to 6 living in the same household
Not Eligible

You will not qualify if you...

  • Diagnosis of major chronic diseases such as severe respiratory diseases, cardiovascular diseases, malignant tumors, or end-stage renal disease
  • Pregnant or breastfeeding women
  • Current smokers or those exposed to occupational dust or hazards
  • Unable to understand the study process or communicate effectively due to psychiatric disorders, severe neuroses, or other reasons preventing cooperation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Suiping County Health Center

Zhumadian, Henan, China, 4630000

Not Yet Recruiting

2

Hong'an County Health Center

Huanggang, Hubei, China, 438000

Actively Recruiting

3

Longhui County Health Center

Shaoyang, Hunan, China, 422000

Not Yet Recruiting

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Research Team

K

Kuai Yu

CONTACT

H

Hao Wang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

PREVENTION

Number of Arms

4

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