Actively Recruiting
Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: A Prospective Study
Led by Chin-Wei Huang · Updated on 2026-04-13
200
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective study aims to evaluate the effects of mega-dose vitamin D pulse therapy followed by maintenance therapy on seizure frequency, fatigue, and quality of life in patients with epilepsy. Participants will receive vitamin D supplementation, and clinical outcomes will be assessed over time to determine its potential benefits on seizure control and patient-reported outcomes.
CONDITIONS
Official Title
Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: A Prospective Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 20 or above (inclusive)
- Diagnosed with epilepsy (refractory epilepsy defined as use of more than two drugs without good seizure control at standard doses)
- No imaging evidence of persistent or expanding brain damage in the past three years
- Ability of subjects or family members (caregivers) to comply with trial plan and take vitamin D
You will not qualify if you...
AI-Screening
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Trial Site Locations
Total: 1 location
1
National Cheng Kung University Hospital
Tainan, Taiwan, 704
Actively Recruiting
Research Team
S
Shiue Yu Chen, Master
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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