Actively Recruiting

Phase Not Applicable
Age: 55Years +
All Genders
Healthy Volunteers
NCT07186023

Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas

Led by National Health Research Institutes, Taiwan · Updated on 2025-09-22

124

Participants Needed

2

Research Sites

174 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This randomized controlled trial will examine the effects of mindfulness-based interventions and brain stimulation interventions on cognitive function and psychological well-being in older adults. The study will employ a comprehensive assessment approach incorporating psychological evaluations, behavioral assessments, psychophysiological measurements, and neuroimaging analyses to characterize the outcome of nonpharmaceutical interventions in improving geriatric well-being or reducing depression severity.

CONDITIONS

Official Title

Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas

Who Can Participate

Age: 55Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 55 years or older
  • Literate or educated above elementary school level
  • Normal or corrected vision and hearing, able to communicate and understand explanations
  • Right-handed as assessed by the Edinburgh Handedness Inventory
  • For brain stimulation group: diagnosed with major depressive disorder by a psychiatrist and prescribed brain stimulation therapy
  • Ability to cooperate with psychiatric outpatient clinic regulations
Not Eligible

You will not qualify if you...

  • Diagnosis of dementia, stroke, cerebrovascular disease, brain injury, epilepsy, or Parkinson's disease
  • Presence of neurological system disorders
  • Alcohol or drug dependence
  • Major physical illnesses such as diabetes, heart failure, endocrine abnormalities, or recent acute myocardial infarction within past three months
  • Presence of metal objects incompatible with MRI (e.g., pacemakers, vascular clips, hearing aids, artificial joints, steel pins)
  • Claustrophobia
  • Pregnancy or possibility of pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Shuang Ho Biomedical Park, Taipei Medical University

New Taipei City, Taiwan, 235603

Actively Recruiting

2

National Center for Geriatrics and Welfare Research

Yunlin, Taiwan, 632007

Not Yet Recruiting

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Research Team

A

Ai-Ling Hsu, PhD.

CONTACT

C

Changwei W. Wu, PhD.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

4

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