Actively Recruiting
Effects of Mindfulness Meditation in Virtual Reality on Craving and Smoking Cessation
Led by Centre Hospitalier Henri Laborit · Updated on 2026-01-13
200
Participants Needed
3
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Investigators seek to propose a non-drug therapeutic alternative, namely a mindfulness meditation protocol based on virtual reality training in order to induce progressive modifications of various indicators of craving. The study hypothesis is that the practice of mindfulness meditation in a virtual reality environment reduces the craving induced by cues and stress and therefore ultimately smoking relapse. The main objective of the protocol will be to demonstrate that mindfulness meditation can reduce long-term relapse (continuous cessation (\> 30 days) of smoking cessation). The participants will be randomized into two groups: the experimental group will perform six virtual reality sessions in a multisensory cabin at the rate of one session per week; the control group will be prescribed the gold standard treatment (nicotine patches and chewing gum). Participants will be seen again at three and six months to assess whether or not there has been a smoking relapse.
CONDITIONS
Official Title
Effects of Mindfulness Meditation in Virtual Reality on Craving and Smoking Cessation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Smoking 10 to 40 cigarettes per day
- Men or women aged 18 to 75 years inclusive
- Diagnosed with substance use disorder according to DSM5
- Covered by social security or eligible through a third party as per French law on human research
- Provided signed informed consent after receiving written information
You will not qualify if you...
- Disabling cognitive disorders
- Under 18 or over 75 years old
- Psychological or psychiatric disorder requiring specialized follow-up
- Addiction to substances other than tobacco
- Cardiological conditions detected by ECG that could affect participation (for experimental group)
- Advanced pulmonary, renal, hepatic diseases, or other serious unstable medical conditions judged by doctor
- Pregnant or breastfeeding women
- Participating in another clinical trial simultaneously
- Employees of the investigator or trial site
- Legally protected individuals
- Do not speak French
- Not covered by state health insurance
- Unable to complete study questionnaires
- Claustrophobic or anxious about using the virtual reality cabin
- Allergic to any component in nicotine substitutes
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Cabinet Médical
Iteuil, France
Actively Recruiting
2
Cabinet médical des Couronneries
Poitiers, France
Actively Recruiting
3
Centre Hospitalier Henri Laborit
Poitiers, France
Actively Recruiting
Research Team
N
Nematollah JAAFARI
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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