Actively Recruiting
Effects of Moderate/Severe Traumatic Brain Injury in the Subacute or Chronic Phase on Locomotor Strategies Involved in Navigation in Complex Virtual Environments
Led by Pôle Saint Hélier · Updated on 2025-11-17
40
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
While clinical assessment of locomotor function in this population is carried out using tasks involving walking in a straight line without any obstacles, it does not take into account ecological situations (i.e., situations comparable to real-life situations) in which the person interacts with their environment, such as walking down a street with other pedestrians, which is fundamental to everyday life. This research therefore aims to study the social navigation skills during locomotion of people who have suffered a moderate or severe head injury in the chronic phase in more ecological tasks. This will provide a better understanding of the difficulties encountered by these patients during locomotor interactions in everyday life.
CONDITIONS
Official Title
Effects of Moderate/Severe Traumatic Brain Injury in the Subacute or Chronic Phase on Locomotor Strategies Involved in Navigation in Complex Virtual Environments
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 55 years old
- Male or female
- For traumatic brain injury group: first non-penetrating head injury with Glasgow Coma Scale score between 6 and 12
- In subacute or chronic phase at least 3 months after injury (for traumatic brain injury group)
- Able to walk at least 20 meters without technical or human assistance with a walking speed of 0.8 m/s or more and a minimum 300 m walking perimeter
- Able to maintain dynamic balance while standing with Timed Up and Go test under 16 seconds
- Able to answer simple questionnaires as judged by the investigator
- Provided free, informed, written consent
- Registered with a social security system
- Individuals under legal guardianship may be eligible (traumatic brain injury group only)
You will not qualify if you...
- Persons under legal protection other than guardianship or unable to give consent (traumatic brain injury group)
- Severe psychiatric care ongoing that may affect study participation
- Neurological signs of neurodegenerative disease causing gait disturbance
- Musculoskeletal disorders affecting walking ability
- Uncontrolled epilepsy at time of inclusion
- Visual impairments making participation impossible as judged by investigator
- Pregnant, parturient, or breastfeeding women
- Participation in another ongoing human research protocol
- For healthy controls: fatigue, trauma, or condition affecting mobility, posture, balance, or walking
- Persons deprived of liberty by judicial or administrative decision
- Persons under legal protection or unable to give consent
- Severe psychiatric treatment or admitted to health or social care facility for non-research reasons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondation Saint Helier
Rennes, France, 35043
Actively Recruiting
Research Team
E
Emilie Leblong, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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