Actively Recruiting
Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract
Led by University of California, Irvine · Updated on 2025-12-17
200
Participants Needed
1
Research Sites
326 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research study is to identify the effects of 2 over-the-counter mouthwashes on bacteria and 3 viruses in the participant's mouth and gut. The participant will be randomly allocated to rinse their mouth twice daily either with Listerine mouthwash, Lumineux Oral Essentials mouthwash, or water. The overall duration of the study will be approximately 180 days and will include approximately 5 visits and 15-30 minutes for each visit with a total of approximately 2.5 hours of your time. Additionally, fecal matter will also be collected in some subjects using a commercial collection kit.
CONDITIONS
Official Title
Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Eligible men and non-pregnant and non-lactating women of all races aged 18-25
- Volunteers must consent to participate in all scheduled exam visits and procedures
- Volunteers must be available for follow-up on the telephone
- Healthy gums or gums that bleed when you brush them
You will not qualify if you...
- Volunteers unable or unwilling to sign the informed consent form
- Having less than 20 teeth (excluding third molars)
- Use of antibiotics in the previous 3 months
- Any condition or situation at baseline that might prevent compliance with study requirements or affect data quality as judged by the Principal Investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beckman Laser Institute and Medical Clinic
Irvine, California, United States, 92612
Actively Recruiting
Research Team
N
Nicole Wakida, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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