Actively Recruiting
Effects of Nasal Airflow on Sleep in Tracheotomized Patients
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-07-03
24
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The passage of air through the nasal cavities generates rhythmic oscillations transmitted by the olfactory bulb to the brain, which induces cerebral activation in functional brain areas and is associated with better cognitive performance compared to oral breathing. Consequently, the abolition of nasal ventilation - intrinsic in tracheotomized and ventilated patients - could have deleterious effects on brain activity. Besides the loss of olfaction, the abolition of nasal ventilation could affect brain activity and sleep. The hypothesis of the present study is that the restoration of nasal stimulation by the passage of humidified nasal airflow in tracheotomized and ventilated patients improves sleep quality, notably with a greater proportion of time spent in REM sleep.
CONDITIONS
Official Title
Effects of Nasal Airflow on Sleep in Tracheotomized Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Admission to PRRS for weaning from ventilation
- Tracheotomy and nocturnal invasive mechanical ventilation
- Indication for polysomnography by care team
- Agreement to participate by patient or trusted person/relative and signature of consent form
- Affiliation with a social security scheme or beneficiary
You will not qualify if you...
- Diseases of the central nervous system such as cerebrovascular accident, multiple sclerosis, or epilepsy
- Psychiatric illnesses including psychoses
- Hyperthermia with temperature above 38.5°C
- Agitation or resuscitation delirium
- Continuous use of sedatives
- Patients under legal protection (guardianship or curatorship)
- Patients deprived of liberty by judicial or administrative decision
- Patients under AME
- Pregnant or breast-feeding women
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Pitié Salpétrière HOSPITAL
Paris, Paris, France, 75013
Actively Recruiting
Research Team
M
Martin Dres, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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