Actively Recruiting
Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell Carcinoma
Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2024-08-28
306
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to learn about the Effects of neoadjuvant therapy with carboplatin, paclitaxel combined with anti-PD-1 drugs on cognitive function in patients with resectable head and neck squamous cell carcinoma: a prospective cohort study
CONDITIONS
Official Title
Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with head and neck squamous cell carcinoma (stage I-IVA), untreated, and planned for surgery alone or surgery plus chemotherapy and immunotherapy
- Able to speak Chinese and have some reading and writing skills
- Healthy dental inpatients without oral cancer, neurological diseases, or history of malignant tumors (for healthy group)
You will not qualify if you...
- Brain tumor, brain injury, or stroke at baseline or during follow-up
- History of stroke or medical conditions with high risk for dementia or recurrence
- Active mental illness or active narcotic drug use, including alcohol use more than 4 times daily or weekly
- Neurocognitive diseases affecting cognitive function, such as Parkinson's disease or Alzheimer's disease
- History of drug-associated encephalopathy or brain infection
- Changing treatment plan during therapy
- Current or past use of antidepressants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guanzhou, Guangdong, China, 510000
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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