Actively Recruiting
The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia
Led by Centre for Addiction and Mental Health · Updated on 2025-03-28
106
Participants Needed
1
Research Sites
345 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve antipsychotic medication adherence in patients with schizophrenia (SCZ). The investigators hypothesize that 20 sessions of tDCS will improve medication nonadherence in patients with SCZ.
CONDITIONS
Official Title
The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female participants of any race or ethnicity
- Inpatients or outpatients 18 years of age or older
- Diagnosis of schizophrenia or schizoaffective disorder according to DSM-V
- Capable of giving informed consent to participate
- On a stable dose of antipsychotic and other medications for at least 2 months with no expected dose changes during the study
You will not qualify if you...
- Unable or unwilling to consent based on the MacArthur Test of Competence
- Unstable medical condition or major neurological illness including history of seizures
- Acute suicidal or homicidal thoughts
- High formal thought disorder rating (score 3 or more on PANSS P2 item)
- Substance dependence (except caffeine and nicotine) within 1 month before study entry
- Positive urine drug screen (except cannabis/marijuana) at screening
- Metal implants, pacemaker, or other reasons preventing MRI scans
- Pregnancy
- Score below 32 on the Wide Range Achievement Test-III
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre for Addiction and Mental Health
Toronto, Ontario, Canada, M5T 1R8
Actively Recruiting
Research Team
P
Philip Gerretsen, MD, PhD
CONTACT
A
Ariel Graff, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here