Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05932745

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

Led by Yale University · Updated on 2025-12-26

66

Participants Needed

1

Research Sites

45 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is an examination of the influence of cooling components of WS-3, WS-23, and menthol on the appeal and addiction potential of nicotine-containing e-liquids among adults.

CONDITIONS

Official Title

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Able to read and write
  • Current e-cigarette user
  • Urine cotinine level  200 ng/ml
  • Willing to abstain from tobacco/nicotine use for 2 hours before sessions
Not Eligible

You will not qualify if you...

  • Current use of non-prescription substances other than nicotine, marijuana, or alcohol
  • Significant current medical or psychiatric condition
  • Known allergy to propylene glycol
  • Pregnant or breastfeeding
  • Uncontrolled asthma
  • Allergy to nuts or e-liquid flavorings
  • Current marijuana vaping and symptoms of E-cigarette or Vaping Use Associated Lung Injury (EVALI)
  • Dislike of menthol flavor

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

JB Pierce Lab

New Haven, Connecticut, United States, 06519

Actively Recruiting

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Research Team

D

Danielle Davis, PhD

CONTACT

W

Wei Li, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

18

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Effects of Novel E-cigarette Constituents on Adults TCORS 3.0 | DecenTrialz