Actively Recruiting

Phase Not Applicable
Age: 20Years - 65Years
All Genders
Healthy Volunteers
NCT05402761

Effects of Nurse-Guided BBTi for Improving Insomnia : in Patients at the Recovery Following Traumatic Brain Injury

Led by Taipei Medical University · Updated on 2026-03-31

93

Participants Needed

2

Research Sites

224 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

nsomnia is a frequent complaint reported by patients with TBI, and exacerbates their ability to return to productive activity, which subsequently elevate related healthcare costs and burden. Existing literatures found that effects of CBTi, first-line therapy for insomnia, on post-traumatic insomnia is still debated, indicating that developing an alternative nonpharmacological therapy for alleviating insomnia following TBI is required. Besides, digital health is one of strategies to achieve precision health. Thus far, knowledge regarding whether mobile-delivered BBTi has non-inferiority effects as BBTi in treating insomnia is still lacking. Therefore, a RCT with a large sample size to examine the immediate and lasting effects of BBTi and mobile-delivered BBTi on insomnia, mood disturbances, and cognitive dysfunctions in patients following TBI at the recovery stage compared with the control participants.

CONDITIONS

Official Title

Effects of Nurse-Guided BBTi for Improving Insomnia : in Patients at the Recovery Following Traumatic Brain Injury

Who Can Participate

Age: 20Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Have received a diagnosis of traumatic brain injury at least 3 months before enrollment
  • Had an initial Glasgow Coma Scale (GCS) score of 3-15 and a GCS score of 15 at enrollment
  • Experience lying awake for 30 or more minutes at night for at least 3 nights per week for 3 months or longer
  • Have post-TBI insomnia with an insomnia severity scale score greater than 7 at screening
  • Are able to communicate in Mandarin Chinese and complete cognitive tasks with a Rancho Los Amigos cognitive functioning score above 9
Not Eligible

You will not qualify if you...

  • Have premorbid diagnoses of seizure
  • Have other sleep disorders such as sleep apnea with a STOP-Bang questionnaire score above 3
  • Have psychiatric diseases
  • Have substance abuse or alcoholism
  • Are shift workers
  • Are women who are pregnant, breastfeeding, or in menopausal transition

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Taipei Medical University

Taipei, Taiwan, 110

Actively Recruiting

2

Skin Kong International Health Center

Taipei, Taiwan, 111

Actively Recruiting

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Research Team

H

Hsiao-Yean Chiu, Ass. Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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