Actively Recruiting

Phase Not Applicable
Age: 35Years - 65Years
All Genders
Healthy Volunteers
NCT07345260

The Effects of a Nutritional Supplement on Sleep Quality

Led by Athletic Greens International · Updated on 2026-02-10

140

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a randomized, double-blind, placebo-controlled study of N=140 adult men and women with sub-clinical sleep issues. This study to assess the effect of a novel dietary supplement on sleep related outcomes.

CONDITIONS

Official Title

The Effects of a Nutritional Supplement on Sleep Quality

Who Can Participate

Age: 35Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be male or female
  • Be aged 35-65
  • Body Mass Index between 18.5 and 29.9 kg/m2
  • Currently experiencing issues with falling asleep, staying asleep, or waking up during the night
  • Score of 7 or less on the RU-SATED validated sleep questionnaire
  • Willing to follow the study protocol
  • Willing to stop using other sleep-related supplements, medications, or herbal remedies during the study
  • Agree to limit alcohol intake within approximately 4 hours of bedtime
  • Agree to limit caffeine intake to 400 mg/day or less and avoid caffeine after 2:00 PM during the study
  • Generally healthy without uncontrolled chronic disease
  • Resides in the United States
Not Eligible

You will not qualify if you...

  • Diagnosed chronic sleep conditions such as insomnia, narcolepsy, REM Behavior Disorder, moderate to severe restless leg syndrome, or sleep apnea
  • Women currently undergoing perimenopause or experiencing vasomotor symptoms like night sweats
  • Use of hormone therapy within the last 3 months
  • Diagnosed psychiatric disorders with active symptoms including major depressive disorder, bipolar disorder, generalized anxiety disorder, PTSD with frequent nightmares
  • Diagnosed neurodegenerative diseases or chronic pain disorders such as Parkinson's disease, Alzheimer's disease, or uncontrolled fibromyalgia
  • Regular use of prescribed stimulant medications like amphetamines, methylphenidate, or modafinil/armodafinil
  • Current use of CNS activating antidepressants including Bupropion, Fluoxetine, Venlafaxine, or Sertraline
  • Use of cannabis or THC-containing products within the past 30 days
  • Jobs disrupting nighttime sleep such as night or third shift work or excessive travel
  • Unwillingness to wear the Oura ring device or use its app regularly during the study
  • Current use of prescription sleep aids
  • Introduction of new supplements, medications, or herbal remedies for sleep during the study
  • Allergies or sensitivities to any study product ingredients
  • Women who are pregnant, breastfeeding, or trying to conceive during the study
  • History of substance abuse
  • Heavy alcohol consumption (8+ drinks per week for women, 15+ drinks per week for men)
  • Participation in another research study during this study's duration

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Citruslabs

Santa Monica, California, United States, 90404

Actively Recruiting

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Research Team

P

Principal Investigator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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