Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05015348

Effects of Omega-3 PUFA on Lipids, Inflammatory Factors and Body Composition in Patients with Hyperlipidemia

Led by Peking Union Medical College Hospital · Updated on 2025-01-01

120

Participants Needed

1

Research Sites

160 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients with hyperlipidemia will be allocated into intervention or control group randomly. Participants of intervention group will be provided with Omega-3 PUFA, while participants of control group will be provided with placebo which looked same as the drug of intervention group. During the study, all participants can have nutritional counseling and education for low-fat diet. The lipids, inflammatory factors, weight, and body composition will be assessed and recorded before, at the middle, and end of the study.

CONDITIONS

Official Title

Effects of Omega-3 PUFA on Lipids, Inflammatory Factors and Body Composition in Patients with Hyperlipidemia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female, 18 years old and above
  • Diagnosed with hyperlipidemia meeting clinical criteria: triglycerides ≥1.7 mmol/L, or total cholesterol ≥5.2 mmol/L, or LDL cholesterol ≥3.4 mmol/L
  • Fully understand and voluntarily sign informed consent
  • Able to eat orally
  • Able to follow the research protocol and comply with doctor and researcher instructions
Not Eligible

You will not qualify if you...

  • Currently receiving lipid-lowering drugs
  • Hyperlipidemia caused by secondary conditions such as nephrotic syndrome, hypothyroidism, renal failure, liver disease, systemic lupus erythematosus, glycogen storage disease, myeloma, fat atrophy, acute porphyria, polycystic ovary syndrome, or use of certain medications causing secondary dyslipidemia
  • Severe diseases including heart, liver, kidney dysfunction, recent acute myocardial infarction, stroke, intracerebral hemorrhage, acute COPD attack, respiratory failure within 3 months; recent surgery within 3 months; or deemed unsuitable by clinician
  • Hemorrhagic disease or bleeding tendency
  • History of allergy to omega-3 polyenoic acid preparations
  • Pregnant or lactating women
  • Poor compliance or inability to complete follow-up
  • Serious abnormal metabolism or need for further intervention making continued participation unsuitable as assessed by physician

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking Union Medical College Hospita

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

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Research Team

K

Kang Yu, master

CONTACT

F

Fang Wang, master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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