Actively Recruiting

Phase Not Applicable
Age: 30Years - 70Years
All Genders
Healthy Volunteers
NCT06072066

Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

Led by Integrative Skin Science and Research · Updated on 2024-08-27

24

Participants Needed

1

Research Sites

57 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate how supplementation will alter the skin and the gut barrier and inflammation in those with rosacea.

CONDITIONS

Official Title

Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

Who Can Participate

Age: 30Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females 30 to 70 years of age
  • Presence of mild to moderate rosacea (erythematotelangiectatic or papulopustular)
  • High sensitivity C-reactive protein (hs-CRP) level greater than or equal to 1.0 mg/L
Not Eligible

You will not qualify if you...

  • Severe rosacea as noted by investigator global assessment
  • Unwillingness to stop oral supplements or ingredients found in the study supplement 1 month before enrollment
  • Unwillingness to stop oral L-glutamine or L-glutamine containing supplements 1 month before enrollment
  • Unwillingness to stop topical benzoyl peroxide or retinoids 2 weeks before enrollment
  • Unwillingness to keep facial regimen unchanged during the study
  • Use of oral antibiotics within the past month
  • Pregnancy or breastfeeding
  • Hormonal contraception or therapy changes within 3 months before joining
  • Use of oral contraceptive pills or progesterone or estrogen containing therapies
  • Use of isotretinoin within 3 months prior to enrollment
  • Use of finasteride or dutasteride
  • Current smoker, smoker within past year, or more than 5 pack-year smoking history

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Integrative Skin and Research

Sacramento, California, United States, 95815

Actively Recruiting

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Research Team

C

Caitlin Egli

CONTACT

M

Milred Min

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea | DecenTrialz