Actively Recruiting
Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease
Led by University of Minnesota · Updated on 2026-01-26
24
Participants Needed
1
Research Sites
540 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted dorsal GP stimulation is shown to significantly improve motor features that are typically resistant to dopamine replacement therapy, these experiments will likely have major impact on clinical practice by providing a potential strategy to these medically intractable symptoms.
CONDITIONS
Official Title
Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of idiopathic Parkinson's disease
- Have undergone neurosurgery to implant deep brain stimulators in the globus pallidus or subthalamic nucleus
- Existing 7T brain imaging
You will not qualify if you...
- History of musculoskeletal disorders significantly affecting movement of upper or lower limbs
- Other significant neurological disorders
- History of dementia or cognitive impairment as assessed by UBACC or MacCAT-CR
- Post-operative complications or adverse effects
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Of Minnesota
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
Research Team
C
Colum MacKinnon, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here