Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
All Genders
Healthy Volunteers
NCT06679543

Effects of Partial Sleep Deprivation on Cardiac Output During Cycling

Led by University of Guelph · Updated on 2026-04-28

30

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are: * Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation? * Do sex differences exist? Participants will: * Visit the lab after a night of normal sleep and a night of partial sleep deprivation. * Keep a daily diary of their sleep and food/beverage intake. * Perform maximal and submaximal exercise on a cycle ergometer.

CONDITIONS

Official Title

Effects of Partial Sleep Deprivation on Cardiac Output During Cycling

Who Can Participate

Age: 18Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Free of known cardiovascular or metabolic diseases or sleep disorders
  • No history of smoking within the past 3 months
  • Able to engage in physical activity as assessed by the physical activity readiness questionnaire (PAR-Q+)
  • No prescription of chronic medications other than oral contraceptives
  • Able to abide by sleep protocols for all visits
  • Not allergic to ultrasound gel
  • Not pregnant
Not Eligible

You will not qualify if you...

  • Diagnosed with cardiovascular or metabolic disease or sleep disorders
  • History of smoking within the past 3 months
  • Not ready to engage in physical activity as assessed by the PAR-Q+
  • Prescribed chronic medications other than oral contraceptives
  • Unable to abide by sleep protocols for any testing visit
  • Allergic to ultrasound gel
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Guelph

Guelph, Ontario, Canada, N1G 2W1

Actively Recruiting

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Research Team

J

Julian Bommarito, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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Effects of Partial Sleep Deprivation on Cardiac Output During Cycling | DecenTrialz