Actively Recruiting
Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands
Led by University of California, Davis · Updated on 2025-12-05
75
Participants Needed
1
Research Sites
324 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to better understand the neural correlates of higher-order cognition, both in the healthy brain and in schizophrenia, and to determine how these mechanisms are modulated by transcranial direct current stimulation (tDCS) at frontal and occipital scalp sites. Testing the effects of tDCS at these scalp sites on cognitive task performance will help us understand the roles of the brain regions corresponding to these sites during higher-order cognitive processing (language comprehension, cognitive control, and related attention and memory processes). Behavioral and electrophysiological (EEG) measures will be used to assess cognitive performance. Our overarching hypothesis is that stimulating prefrontal circuits with tDCS can improve cognitive control performance, and ultimately performance on a range of cognitive tasks, as compared to stimulating a different cortical region (occipital cortex) or using sham stimulation. This study is solely intended as basic research in order to understand brain function in healthy individuals and individuals with schizophrenia. This study is not intended to diagnose, cure or treat schizophrenia or any other disease.
CONDITIONS
Official Title
Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between ages 18 and 50
- Able to speak and understand English well enough to complete cognitive tasks
- Able to give valid informed consent
You will not qualify if you...
- History of head trauma
- Current or past treatment with psychotropic medication
- Vision corrected worse than 20/30
- Contraindications to tDCS or MRI such as pregnancy, metal in the body, serious medical conditions, claustrophobia, metallic implants, skin damage or conditions like eczema at electrode sites, cranial pathologies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Imaging Research Center
Sacramento, California, United States, 95817
Actively Recruiting
Research Team
M
Minhtrang Chu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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