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Study of Physical Exercise and a Nutritional Supplement to Improve Body Composition and Metabolic Health in Adults Aged 50 to 65 with Metabolic Challenges but Not Obese
Led by University of Valencia · Updated on 2026-05-04
70
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the effects of physical exercise combined with a nutritional supplement on body composition, metabolic function, and overall health in adults aged 50 to 65 years who have metabolic challenges but are not clinically obese. The study focuses on adults with overweight BMI 25.0 to 29.9 kgm who exhibit mild metabolic dysfunction, such as altered body fat, abnormal glucose or lipid markers, or low physical activity. This trial aims to identify targeted interventions for this growing population at increased cardiometabolic risk despite non-obese BMI status. The study is a 12-week randomized, controlled, triple-blind clinical trial with two parallel groups. One group receives a multicomponent functional exercise program combined with a daily oral thermogenic and appetite-modulating nutritional supplement called phenylcapsaicin. The other group receives the same exercise program and a placebo supplement identical in appearance but without the active ingredient. Both groups follow a standardized dietary control plan to isolate the supplements specific effects. Participants will attend supervised exercise sessions three times per week, each lasting 60 minutes, featuring joint mobility, strength, coordination, and agility exercises. Before and after the 12-week intervention, researchers will assess body composition using dual-energy X-ray absorptiometry DXA, metabolic and hormonal biomarkers, aerobic and strength capacity, and quality of life, sleep, and appetite through validated questionnaires. These measures will help evaluate changes in fat distribution, metabolic function, and overall health in this metabolically challenged adult population.
CONDITIONS
Brief Title
Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in Adults With a Metabolically Challenging Profile
Research Team
J
Juan Carlos Colado Sánchez, Chair full professor
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