Actively Recruiting
Effects of a Placebo Probiotic on Gut Health and General Well-being in Individuals With Mild Gastrointestinal Symptoms
Led by Catholic University of the Sacred Heart · Updated on 2024-12-06
30
Participants Needed
1
Research Sites
18 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The present study is aimed at exploring whether positive expectations of receiving a three-week treatment with a probiotic supplement (in fact a placebo) improve symptoms of gastrointestinal distress and promote physical and emotional well-being in healthy individuals with mild gastrointestinal symptoms. At first, a comparison is planned between (1) a classic deceptive placebo manipulation (Deceptive Placebo group, DP), and (2) a control condition (Control group, C), in which no placebo substance will be administered. After the three-week waiting list, the Control group will be invited to take the placebo probiotic pills in an "open-label" fashion (Open Label Placebo, OLP). Specifically, participants will be informed that the pills are inert placebos. An exploratory analysis will help to clarify whether the OLP paradigm leads to significant effects, based on a within-group (C- OLP) and between-group comparison (DP-OLP).
CONDITIONS
Official Title
Effects of a Placebo Probiotic on Gut Health and General Well-being in Individuals With Mild Gastrointestinal Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 20 and 65 years
- Individuals with mild gastrointestinal symptoms such as digestive issues, acid reflux, or constipation, without severe impact on daily activities
You will not qualify if you...
- Diagnosis of functional gastrointestinal disorders such as irritable bowel syndrome, ulcerative colitis, or chronic inflammatory bowel diseases
- Presence of neurodegenerative diseases or psychiatric conditions
- Currently taking probiotic supplements at enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Catholic University of the Sacred Heart
Milan, Italy, 20123
Actively Recruiting
Research Team
D
Diletta Barbiani
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here